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January 15, 2026
8 min read

Subdermal Laser vs. RF Microneedling: Understanding the Key Differences

technologyeducationskin tighteningcomparison
O

Onyxa Medical

Clinical Education Team

Patients exploring non-surgical skin tightening have more options than ever. Two of the most discussed technologies are subdermal laser tissue remodeling and radiofrequency (RF) microneedling. While both aim to improve skin quality and tightness, they differ fundamentally in mechanism of action, depth of treatment, clinical evidence, and expected outcomes.

Mechanism of Action

RF microneedling devices (such as Morpheus8, Potenza, and Genius) deliver radiofrequency energy through an array of fine needles that penetrate the skin to a maximum depth of approximately 4mm. The RF energy heats the surrounding tissue, creating micro-injuries that stimulate a wound healing response. Subdermal laser, by contrast, delivers laser energy directly to the subdermal plane through ultra-thin fiber optics inserted beneath the skin. This allows energy delivery at the exact tissue depth where collagen remodeling and fat reduction are most effective — well beyond the 4mm limit of microneedling devices.

Depth and Precision

This difference in delivery depth is clinically significant. RF microneedling treats the superficial dermis and upper reticular dermis. Subdermal laser reaches the deep dermis, subdermal fat layer, and fibroseptal network — the structural framework that determines skin tightness and contour. The fiber optic delivery system (400–800μm diameter) allows providers to treat specific tissue planes with precision that surface-based energy devices cannot match.

Treatment Sessions

RF microneedling typically requires 2–3 treatment sessions spaced 4–6 weeks apart to achieve optimal results. Each session involves downtime of 2–5 days. Subdermal laser achieves clinically significant results in a single treatment session, with 3–10 days of recovery. When comparing total downtime and time-to-result, subdermal laser often provides a more efficient treatment pathway.

Clinical Evidence

Subdermal laser tissue remodeling is supported by over 15 peer-reviewed clinical publications with objective biometric measurements. Published data includes 48.75% dermis density increase, 53.78% wrinkle volume decrease, and 36.9% dermis thickness increase (Nilforoushzadeh et al., Journal of Cosmetic Dermatology, 2023). A systematic review of 31 studies confirmed the efficacy and safety profile of the technology (Elicit Research, 2024). RF microneedling has its own body of evidence, though comparative studies suggest that subdermal delivery produces more significant tissue remodeling than transcutaneous approaches.

Safety Considerations

Both technologies have established safety profiles when used by trained providers. Subdermal laser has a notable advantage for patients with darker skin types: because the energy is delivered beneath the epidermis, there is no risk of epidermal damage, burns, or post-inflammatory hyperpigmentation. This makes it safe for all Fitzpatrick skin types (I–VI). RF microneedling, while generally safe, carries some risk of post-inflammatory hyperpigmentation in darker skin types due to the transcutaneous energy delivery.

Fat Reduction Capability

A key differentiator is the ability to address fat volume. RF microneedling is primarily a skin tightening technology — it does not significantly reduce fat. Subdermal laser platforms with the 980nm wavelength can perform targeted thermal lipolysis, reducing fat volume while simultaneously tightening skin with the 1470nm wavelength. This dual capability is particularly valuable for areas like the submental region (double chin), jawline, and body contouring.

Making the Right Choice

The choice between these technologies depends on the patient's specific concerns, the degree of laxity, and their treatment goals. RF microneedling may be appropriate for patients with mild skin texture concerns and minimal laxity who prefer a less invasive approach. Subdermal laser is better suited for patients with moderate to significant laxity, those who want fat reduction combined with tightening, and those seeking more dramatic single-session results. Many practices offer both technologies to serve the full spectrum of patient needs.

Individual results vary, and patients should consult with a qualified provider to determine the most appropriate treatment approach for their specific anatomy and goals. The information in this article is for educational purposes and should not replace professional medical advice.

Individual results may vary. The information provided is for educational purposes only and should not be considered medical advice. Consult with a qualified healthcare provider to determine if any treatment is appropriate for your specific needs. Junera is FDA-cleared for soft tissue coagulation and ablation (K212734). Aesthetic benefits described are supported by published clinical studies.